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1996-02-27
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Document 0067
DOCN M9630067
TI [Mycobacterium kansasii infection in patients with human
immunodeficiency virus infection]
DT 9603
AU Boudon P; Le Pennec MP; Malbec D; Mathieu M; Slama JL; Manet P; Pines E;
Kretz S; Giacomini T; Service de medecine interne, Hopital
Robert-Ballanger,; Aulnay-sous-Bois, France.
SO Rev Med Interne. 1995;16(10):747-51. Unique Identifier : AIDSLINE
MED/96099702
AB We report a retrospective study of 12 caucasian men infected with HIV
who had developed Mycobacterium kansasii infection (Mk). All patients
had a low blood lymphocyte CD4 count (1-130, mean 15/mm3) and ten met
the diagnostic criteria for AIDS. The 12 patients had pulmonary symptoms
(dyspnea, cough) and fever. On chest X-ray, nodular, interstitial or
diffuse parenchymal infiltrates, mediastinal and hilar adenopathies were
observed. Two patients had pleural effusion, but none had cavitary lung
disease. Mk was isolated by culture of sputum (n = 7), blood (n = 3),
bronchial biopsy (n = 2) or bone marrow (n = 1). No patient had clinical
extra-pulmonary disease. Survival after diagnosis was in average 7
months. Potential for therapeutic response is reviewed and documented.
DE Adult Antitubercular Agents/THERAPEUTIC USE *AIDS-Related
Opportunistic Infections/DRUG THERAPY/MORTALITY English Abstract Human
Male Middle Age Mycobacterium Infections, Atypical/DRUG
THERAPY/*ETIOLOGY/ MORTALITY Retrospective Studies Time Factors
JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).